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Dual Use Therapeutics for Cryptosporidiosis, Toxoplasmosis, and Neosporosis

Cryptosporidium spp are a major cause of prolonged disabling diarrhea both in newborn farm animals and children up to 2 years old, and there are no efficacious drugs available now for Cryptosporidium treatment. Toxoplasma gondii causes disabling primary infection, and can endanger the fetus of pregnant women and farm animals and Neospora caninum causes epidemic abortion in cattle and over $1.2 billion in world-wide economic losses to the cattle industry. This proposal is to test drug candidates, developed in another NIAID funded project, for cryptosporidiosis, toxoplasmosis, and neosporosis to the point where they can be developed as a dual therapy for human and farm animal use.

Active Dates 
09/24/2014 to 06/30/2019
Faculty Involved