• Clinical Professor, Global Health

Executive Director, HIV Vaccine Trials Network
Fred Hutchinson Cancer Research Center
1100 Eastlake Ave, East, 3rd Floor
Seattle, WA 98102
United States

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Dr. James Kublin is currently Executive Director of the HIV Vaccine Trials Network and the COVID-19 Prevention Network based at Fred Hutch. He is also the Medical Director of the Malaria Clinical Trials Center and a faculty member in the Department of Global Health at the University of Washington. Dr. Kublin has conducted extensive research on HIV, TB and malaria, including clinical trials of novel therapies and vaccines. Jim has a long history working with disadvantaged and refugee populations in South and Central America, Southeast Asia and Africa. He was a faculty member at the University of Malawi, College of Medicine, and provided training throughout Africa on epidemiology, malaria, and HIV. Jim continued work in vaccine development and molecular epidemiology while attending the University of Maryland’s School of Medicine for his fellowship in Vaccinology at the Center for Vaccine Development. BMGF awarded Jim a Grand Challenges Exploration award to apply high-throughput system analyses to malaria vaccine development. More recently, Jim is investigating the role of the microbiome in modulating immune responses in HIV and TB vaccine clinical trials and gnotobiotic mouse models.

  • MD (Georgetown University)
  • MPH (Johns Hopkins University)
  • BA (Georgetown University)
  • Spanish
Health Topics 
  • Drug and Vaccine Development
  • Education and Training
  • Epidemiology
  • HIV Transmission
  • Host-Pathogen Interactions
  • Immunizations
  • Infectious Diseases
  • Infectious Diseases (other than STDs)
  • Influenza
  • Innate Immunity
  • Laboratory Strengthening
  • Malaria
  • Molecular Immunology
  • Pathobiology
  • Prevention
  • TB
  • Viruses

Kublin JG, Patnaik P, Jere CS, Miller WC, Hoffman IF, Chimbiya N, Pendame R, Taylor TE, Molyneux, ME. Effect of Plasmodium falciparum malaria on concentration of HIV-1-RNA in the blood of adults in rural Malawi: a prospective cohort study. Lancet. 2005 Jan 15;365(9455):233-40.

Abu-Raddad L, Patnaik P, Kublin JG. Duel Infection with HIV and Malaria Fuels the Spread of Both Diseases in Sub-Saharan Africa. Science, 8 December, 2006.

Cram JA, Fiore-Gartland AJ, Srinivasan S, Karuna S, Pantaleo G, Tomaras GD, Fredricks DN, Kublin JG. Human gut microbiota is associated with HIV-reactive immunoglobulin at baseline and following HIV vaccination. PLoS One. 2019 Dec 23;14(12), 2019.

Baden LR, El Sahly HM, Essink B, et al. Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine. N Engl J Med. 2021 Feb 4;384(5):403-416.

Kublin JG. HIV vaccines beyond COVID-19: merits of trust. J Int AIDS Soc. 2021 May;24(5):e25742. doi: 10.1002/jia2.25742.